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Henry Tedeschi:
Putting molecular cell physiology on the web
Henry
Tedeschi:
Biochemist

Books
Cell
Physiology: Molecular Dynamics, third edition (Minerbi Enterprises, 1998, 1999, 2000).
Mitochondria, Structure and Transducing Function (Springer-Verlag
Vienna, 1976).
Education
Ph.D.,
University of Chicago, 1955
B.S.,
University of Pittsburgh, 1950 |
Biology author Henry
Tedeschi became hooked on biology after reading Charles Darwin's Origin
of the Species in fifth grade. He was an avid reader, especially of
adventure books. In fact, before picking up Origin of Species, young Harold assumed that Darwin's account of his travels in the Beagle might treat him to more adventures. In a way, it did.
Tedeschi was born
in Italy, and lived in Switzerland and Argentina before moving to the
United States when he was 17 to attend the University of Pittsburgh.
Thinking job opportunities would be aplenty, he brought only enough
money to last one year. "To this day I have difficulty in figuring out
why my parents consented to my plans," Tedeschi said. "In those days
travel was not very common -- mostly for financial reasons, one way
from Buenos Aires to New York by airplane was approximately $1,200,
then the price of a car -- and we would be isolated from each other
except for lively correspondence that we always maintained."
After receiving
his bachelor's degree in zoology from the University of Pittsburgh in
1950, Tedeschi went on to the University of Chicago for a doctorate
in physiology. "When I started my research in 1952, the existence of
the cell organelles called mitochondria and their biochemical role --
the main energy suppliers of the cell -- was just beginning to be seriously
recognized," he said. "I showed that they were surrounded by a functional
membrane that could select what molecules went through. In addition,
I made some other observations, one was that one of the mitochondrial
membranes has deep folds like an accordion." He has written more than
70 scientific articles on various physiology topics.
After graduating
from the University of Chicago in 1955, Tedeschi taught at the University
of Illinois Medical School in Chicago and later as at the State University
of New York at Albany where he pioneered the electrical studies of the
mitochondrial membrane. He retired as chair of the department of biological
sciences in 1985 and professor in 1998 at the University of New York
at Albany.
Tedeschi wrote the
first edition of Cell Physiology: Molecular Dynamics, published
by Academic Press, in 1974. Because there was a serious lag between
research and what was taught in medical schools, particularly on the
revolution in genetics and molecular biology, Tedeschi was always writing
material for the graduate students in his department. "This was my contribution
to our graduate program and allowed me to keep up to date," he said.
"At the urging of one of my colleagues, I signed a contract to write Cell Physiology: Molecular Dynamics."
After the first
edition, Academic Press wasn't interested in a second. The rights were
returned to Tedeschi.
In 1993, William
C. Brown published the second edition, but the book was dropped again
when Brown was purchased by Times Mirror. Tedeschi searched again for
another publisher, but then decided to publish it himself -- on the
web.
The web version
of Cell Physiology: Molecular Dynamics, published under the name
Minerbi Enterprises, went online in August 1998. It was the first subscription-based
web book in the field. It is accessed through an ID and password at www.cellphysiology.com.
Tedeschi updates the site just about every day.
"When I started
writing textbooks, there was no such thing as the web," he said. "Now
that it was possible, I thought it would be fun to have a book that
can be updated whenever I felt the need for it. And with a field like
cell biology, you want to update continually, something you can't do
with traditional publishing. For a small publisher, in a rapidly changing
field, this is the way to go."
Some advantages
of web publishing, said Tedeschi, are the ability to revise easily and
keep yourself up-to-date with the field. "It allows me to indulge myself
in topics I would normally not touch," he said. Since retiring, he works
on updating the book full-time.
The 24-chapter web
book has 22 library and class adopters and 300 individual subscriptions,
including some from abroad -- Argentina, Brazil, Chile, Ethiopia, Indonesia,
Japan and Mexico. "It's not clear how many students this represents
because some of the classes are very small and some very large," Tedeschi
said. Subscriptions are $20 for individuals and $100 for libraries or
entire classes. He also allows the subscriptions to be used in multiple
classes from the same institution. "My guess is that the use is modest
-- about 1,500 to 2,000 students per year," he said.
Tedeschi enjoyed
teaching tremendously: "My research, teaching and authoring have been
equally rewarding. It is satisfying to see students' minds move, challenge,
probe." While at SUNY, he developed a new sophomore course in cell biology.
It included essay exams and tests every week. "The improvement from
one set of tests to another was enormous," he said.
Several of his students
went on to become successful in their field. Four became professors,
one at Rensselaer Polytechnic Institute, another at Drake University
and another is at the New York University School of Dentistry.
Tedeschi and Terry
Kershner were married in 1957. They have three children: Alexander,
born in 1958; Devorah, 1959; and David, 1962.
reported
by Kim Pawlak, 2000 |